Postoperative complications after mandibular third molar surgery Dexamethasone, Impacted tooth, Third molar surgery
Conditions
Interventions
2ml of Dexamethasone 8 mg IM injection to buccinator muscle will be injected before the third molar removal procedure after nerve block is obtained. Dexamethasone is a type of steroids which has anti
Experimental Drug,Placebo Comparator Other
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. The volunteer has impacted third molars symmetrically positioned on both sides of the mandible (Class I,II position A, B and C) based on the Pell and Gregory Classification 2. The patients who are not allergic to analgesic (paracetamol) and antibiotic drugs (amoxycillin) 3. The volunteer has provided their consent for the study 4. Age between 18 and 45 years old 5. Healthy volunteer 6. Non-smoker and non alcoholic 7. Volunteers included must have upon presentation bilateral impacted lower third molars, which require flap opening, bone removal and tooth separation during the operation 8. The volunteer is able to understand and carry out the instructions given by the investigators.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or current lactation 2. Volunteers with cardiovascular problems, renal and/or liver failure, or other serious medical condition. 3. Allergic to corticosteroids and local anesthetics 4. Allergic to antibiotics and analgesic drugs 5. Volunteer with facial deformities that may interfere with the injections, surgery or evaluation 6. Swelling and/or infection associated with the third molar site 7. Volunteers taking any medication during the previous 5 days prior to the surgery, that would alter their perception of pain (analgesic, antidepressants) 8. Inability to follow the instructions or cooperate during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-operative swelling before surgery, 2 days after surgery, and 1 week after surgery linear measurement by scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain Immediate after surgery and everyday until next seven days Visual analogue scale (100 mm),Trismus before surgery, 2 days after surgery, and 1 week after surgery Mouth opening linear measurement | — |
Countries
Thailand
Contacts
Public ContactAUNG OO
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mahidol University
Outcome results
None listed