Serum hormonal level and semen parameter in COVID-19 patients at 3, 6, 12 months after infection. COVID-19, Male serum hormone, Semen parameter, Chronic COVID syndrome, male fertility
Conditions
Interventions
Male patients with history of confirmed COVID-19 infection.,Healthy men, without prior history of COVID-19 infection.
For match-pair analysis
Other,Other
COVID-19 Patients,Healthy volunteer
Sponsors
None listed
Eligibility
Sex/Gender
Male
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Male COVID-19 patients hospitalized at KCMH 2. Age 18 y or older 3. Healthy male volunteer, with no previous history of COVID-19 infection. 4. Patients not require additional oxygen supplementation during admission
Exclusion criteria
Exclusion criteria: Male with 1. History of infertility 2. History of testicular trauma, testicular surgery, testicular infection. 3. History of mumps 4. History of testicular tumor or active other malignancy 5. History of cryptorchidism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum testosterone level at 2wk, 3, 6, 12 mo after infection Serum testosterone level, nmol/L,Serum FSH level at 2wk, 3, 6, 12 mo after infection Serum FSH level, IU/L,Serum LH level at 2wk, 3, 6, 12 mo after infection Serum LH level, IU/L,Semen parameter at 3, 12 mo after infection According to WHO laboratory manual for the examination and processing of human semen, 5th edition,Serum AST level at 2wk after infection U/L,Serum ALT at 2wk after infection U/L,ALP at 2wk after infection U/L,Serum albumin level at 2wk after infection g/L,Serum Globulin level at 2wk after infection g/L,Serum Total bilirubin at 2wk after infection mg/dL,Serum Direct bilirubin at 2wk after infection mg/dL | — |
Secondary
| Measure | Time frame |
|---|---|
| IIEF5 Score at 2wk, 3, 6, 12 mo after infection 4 | — |
Countries
Thailand
Contacts
Public ContactPrarch Boonkerd
Division of Urology, Department of Surgery, Faculty of medicine, Chulalongkorn University
Outcome results
None listed