Healthy conditions Pineapple cider vinegar metabolic disorders lipid profiles
Conditions
Interventions
Subjects are received the placebo product which has the same color and smells look like a pineapple cider beverage.,Subjects are received pineapple cider beverage 15 ml/day for 8 weeks.,Subjects are r
Placebo,Pineapple cider beverage 15 ml/day,Pineapple cider beverage 30 ml/day
Sponsors
National Research Council of Thailand (NRCT)
Eligibility
Sex/Gender
All
Age
35 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 35-60 years old 2. Body Mass Index (BMI) more than 23 kg/m2
Exclusion criteria
Exclusion criteria: 1. Volunteers who have been diagnosed with one of the following; cardiovascular diseases, respiratory diseases, neuropsychological diseases, liver disease (AST more than 64 U/L, ALT more than 50 U/L), Kidney disease (estimate GFR less than 90 ml/min), autoimmune disease, hematological disorder, and cancer 2. Volunteers who require supplements or any drug that affect the nervous system by order of the doctor before trial 3. Volunteers who use supplements or any drug that affect the body weight, glucose, and lipid level before trial 4. Smoking more than 10 pieces/ day 5. Drinking alcohol more than 5 times/ day 6. Volunteers who participate in other projects 7. Pregnancy or lactating women 8. Blood pressure less than 140/90 mm Hg and Fasting Blood Sugar (FBS) after fasts for 8 hours less than 126 mg/dL
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolic parameters include Homeostasis Model Assessment Insulin Resistance (HOMA-IR) index, Atherosclerosis index (AI Index) , Atherogenic index of plasma (AIP), and Insulin 8 weeks Laboratory | — |
Secondary
| Measure | Time frame |
|---|---|
| The changes of hematological and clinical chemistry parameters 8 weeks Laboratory,Oxidative stress markers include Malondialdehyde (MDA), Superoxide dismutase (SOD), Catalase (CAT), and Glutathione peroxidase (GSH-Px) 8 weeks Laboratory,Angiotensin converting enzyme (ACE) 8 weeks Elisa method,Advanced glycation end products (AGEs) 8 weeks Elisa method,Urinalysis 8 weeks Laboratory, Homocysteine 8 weeks Laboratory,Body Composition, Body Mass Index (BMI), and Anthropometry 8 weeks Equipment,The changes of electrocardiogram 8 weeks Electrocardiography | — |
Countries
Thailand
Contacts
Public ContactPanakaporn Wannanon
Khon Kaen University
Outcome results
None listed