Total corneal power measured by CASIA 2, Pentacam AXL, and IOLMaster 700 in normal and keratoconus patients CASIA 2, Pentacam AXL, IOLMaster 700, total corneal power, optical biometry, IOL calculation, keratoconus
Conditions
Interventions
Healthy participants at Outpatient unit, Department of Ophthalmology, King Chulalongkorn Memorial Hospital,Keratoconus patients at Outpatient unit, Department of Ophthalmology, King Chulalongkorn Memo
Diagnostic,Diagnostic
Normal group,Keratoconus group
Sponsors
Ratchadapiseksomphot Endowment Fund
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Normal group 1 Healthy participants 2 Age 18 years old or more 3 Able to read, understand and sign an informed consent form Keratoconus group 1 Participants with diagnosed keratoconus by corneal specialist based on both 1.1 Topography or tomography pattern characteristic with abnormal posterior elevation, abnormal corneal thickness 1.2 At least one keratoconus clinical findings on slit lamp examination, corneal stromal thinning, Fleischer ring, and Vogts striae 2 Mild to moderate severity of keratoconus stage 1, 2, 3 by Amsler Krumeich keratoconus classification 3 Subclinical keratoconus or forme fruste keratoconus based on corneal topography pattern characteristic without clinical findings
Exclusion criteria
Exclusion criteria: Normal group 1 Participants who have ocular pathology 1.1 Corneal disease, including severe dry eye, corneal opacity, pterygium 1.2 Retina or macular disease 1.3 Strabismus or nystagmus 2 Previous ocular surgery or refractive surgery 3 Previous ocular trauma Keratoconus group 1 Participants who have ocular pathology 1.1 Other corneal disease 1.2 History of acute hydrops and corneal scarring 1.3 Retina or macular disease 2 Previous ocular surgery or refractive surgery 3 Previous ocular trauma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total corneal power At the day of measurement Agreement between devices by ICC and Bland-Altman plot | — |
Secondary
| Measure | Time frame |
|---|---|
| Total corneal astigmatism At the day of measurement Agreement between devices by ICC and Bland-Altman plot,Anterior keratometry At the day of measurement Agreement between devices by ICC and Bland-Altman plot,Anterior corneal astigmatism At the day of measurement Agreement between devices by ICC and Bland-Altman plot,Posterior keratometry At the day of measurement Agreement between devices by ICC and Bland-Altman plot,Posterior corneal astigmatism At the day of measurement Agreement between devices by ICC and Bland-Altman plot,Anterior chamber depth At the day of measurement Agreement between devices by ICC and Bland-Altman plot,White to white At the day of measurement Agreement between devices by ICC and Bland-Altman plot,Central corneal thickness At the day of measurement Agreement between devices by ICC and Bland-Altman plot,IOL power At the day of measurement Agreement between devices by ICC and Bland-Altman plot | — |
Countries
Thailand
Contacts
Public ContactRusaporn Yodying
Department of Ophthalmology, King Chulalongkorn Memorial Hospital
Outcome results
None listed