Nasal polyp patient need effective topical corticosteroid method for control disease. corticosteroid nasal irrigations, nasal sprays, nasal polyp
Conditions
Interventions
Budesonide respule (0.5mg/2mL) 1 mL + 0.9%NSS 100 ML BID
Nasal spray
0.9%NSS nasal spray 2 puff BID,Nasal irrigation
0.9%NSS 100 ML BID
Nasal spray
Budesonide nasal spray (64mcg/spray) 2 puff BID
Active Comparator Drug,Placebo Comparator Drug
Corticosteroid nasal irrigations ,0.9%NSS nasal irrigation
Sponsors
Faculty of Medicine, Prince of Songkla University,
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Bilateral nasal polyp patient
Exclusion criteria
Exclusion criteria: 1. Previous sinus surgery. 2. Used systemic corticosteroid before 2 weeks, Nasal steroid before 4 weeks, Nasal decongestant before 1 day. 3. Bacterial /Viral/ Fungal rhinosinusitis patient. 4.Patient with systemic conditions Ex. immunodeficiency, autoimmune diseases, cystic fibrosis, mucociliary disorders 5. Patient with pulmonary tuberculosis, DM (uncontrol; Random plasma glucose>200 mg/dL). 6. Patient with severe deviated nasal septum. 7. Patient with steroid allergy, glaucoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nasal polyp size within one month after end of the intervention Nasal polyp grading(0-3) | — |
Secondary
| Measure | Time frame |
|---|---|
| Nasal symptom score within one month after end of the intervention Patient reported outcome using a questionnaire interview | — |
Countries
Thailand
Contacts
Public ContactChakapan Promsopa
Faculty of Medicine, Prince of Songkla University
Outcome results
None listed