Prevention of bacteremia following bony impacted mandibular third molar surgery Mandibular third molar Bacteremia Chlorhexidine mouthrinse Amoxicillin
Conditions
Interventions
Amoxicillin (AMX): 2 g of amoxicillin capsules and sterile distilled water mouthrinse,Chlorhexidine mouthrinse (CHX): 0.3% chlorhexidine (Pharmacy division, Dental Hospital, Faculty of Dentistry, Prin
Active Comparator Drug,Experimental Drug,Placebo Comparator No treatment
AMX group,CHX group,CTR group
Sponsors
Faculty of Dentistry, Prince of Songkla University
Eligibility
Sex/Gender
All
Age
20 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1.Healthy adult patient (20-30 years old) 2.Need of surgical removal of bony impacted mandibular 3rd molar, with partially erupted in oral cavity. 3.No known risk to bacterial endocarditis 4.No signs or symptoms of infection
Exclusion criteria
Exclusion criteria: 1.Patients with current antibiotic treatment in the past 1 month 2.HbA1c level of 6.5% or higher 3.Patients using routine oral antiseptic mouthrinse 4.Patients using immunosuppressant 5.Patient allergic to chlorhexidine or amoxicillin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bacteremia occurrence Before treatment, (BD:0), 30 seconds (BD:1), and 15 minutes (BD:2) following flap incision. BACTEC FX and MALDI-TOF MS | — |
Secondary
| Measure | Time frame |
|---|---|
| Bacteria identification Before treatment, (BD:0), 30 seconds (BD:1), and 15 minutes (BD:2) following flap incision. Gram stain | — |
Countries
Thailand
Contacts
Public ContactSrisurang Suttapreyasri
Prince of Songkla university
Outcome results
None listed