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Comparative outcomes between low molecular-weight heparin combined with mechanical prophylaxis and mechanical prophylaxis alone in thromboprophylaxis in abdominopelvic surgical patients: a randomized control study

Comparative outcomes between low molecular-weight heparin combined with mechanical prophylaxis and mechanical prophylaxis alone in thromboprophylaxis in abdominopelvic surgical patients: a randomized control study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210525006
Enrollment
650
Registered
2021-05-25
Start date
2018-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Venous thromboembolism, including deep vein thrombosis and pulmonary embolism, has become increasingly recognized as a significant public health burden, especially hospital-acquired VTE in patients undergoing major surgery. VTE cancer surgery, DVT prophylaxis, VTE prophylaxis, DVT, PE, deep vein thrombosis, pulmonary embolism, mechanical thromboprophylaxis, intermittent pneumatic compression (IPC), graduated compression stockings (GCS)

Interventions

Intermittent pneumatic stocking and graduated compressive stocking,Low molecular weight heparin, intermittent pneumatic stocking and graduated compressive stocking
Experimental Procedure/Surgery,Placebo Comparator Procedure/Surgery
Study ,Control

Sponsors

Ramathibodi Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: We included all VTE high-risk patients (Caprini risk score > 5) undergoing abdominopelvic surgery between 1 July 2018 and 31 December 2018 in the Departments of General surgery at Ramathibodi hospital, Mahidol University, Bangkok, Thailand. The age of the patients was over 18 years old.

Exclusion criteria

Exclusion criteria: The patients who took anticoagulants or history of DVT or peripheral arterial disease or glomerular filtration rate (GFR) less than 30 ml/min or history of allergic to anticoagulant.

Design outcomes

Primary

MeasureTime frame
Venous thromboembolism 28 days after surgery Venous duplex ultrasound

Secondary

MeasureTime frame
Adverse events 28 days after surgery Review chart and patients interview

Countries

Thailand

Contacts

Public Contactnutsiri kittitirapong

Ramathibodi

nutsiri.kit@mahidol.ac.th.com66855539293

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026