This retrospective study will include adult PD patients at age of above 18 years old from the Thailand Fungal PD-related Infectious Complications Surveillance Data (MycoPDICS DATA) who have fungal peritonitis and catheter-related fungal infection during July 2015-June 2020. To be eligible for inclusion, the patients have to fulfill the diagnosis criteria of the ISPD guideline 2016 by the presence of at least 2 of the following: 1) presence of clinical symptoms of peritoneal inflammation, includi
Conditions
Interventions
The patients who have fungal peritonitis and catheter-related fungal infection and have to fulfill the diagnosis criteria of the ISPD guideline 2016 by the presence of at least 2 of the following: 1)
2) presence of more than 100 leukocytes/mm3 dialysate with at least 50% neutrophils
3) documentation of fungi in dialysate or PD catheter by either smear or culture.,The patients who have fungal peritonitis and catheter-related fungal infection but have not to fulfill the diagnosis c
3) documentation of fungi in dialysate or PD catheter by either smear or culture.,The patients who have bacterial peritonitis and have to fulfill the diagnosis criteria of the ISPD guideline 2016 by t
3) documentation of bacteria in dialysate or PD catheter by either smear or culture.
Fungal peritonitis patients,Fungal colonization without peritonitis patients,Fungal peritonitis patients
Sponsors
The National Research Council of Thailand
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) PD patients with fungal peritonitis 2) Age of above 18 years old from the Thailand Fungal PD-related Infectious Complications Surveillance Data (MycoPDICS DATA) 3) Onset during July 2015-June 2020. T
Exclusion criteria
Exclusion criteria: - Not fulfilling the ISPD Peritonitis Guideline 2016 of diagnostic criteria for peritonitis - No 1-year survival outcome - Mixed fungal infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PD vintage at peritonitis date or have fungal colonization Number of days,PD catheter removal date From peritonitis date or have fungal colonization until catheter removal Number of days,Duration of antifungal therapy From peritonitis date or have fungal colonization until catheter removal Number of days/type/dose,Outcome at 1, 3, 6 and 12 months after peritonitis reported death,Result of cultural organism at date to identify fungus Organism | — |
Secondary
| Measure | Time frame |
|---|---|
| Technical failure at peritonitis date or have fungal colonization Chi-square test and Fishers exact test for categorical data, and Mann-Whitney U test for continuous data,Hospitalization at peritonitis date or have fungal colonization Chi-square test and Fishers exact test for categorical data, and Mann-Whitney U test for continuous data | — |
Countries
Thailand
Contacts
Public ContactTalerngsak Kanjanabuch
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Thailand
Outcome results
None listed