decreasing the heat produced from phacoemulsification tip by using hypothermic irrigation solution will deceased the damage on cornea. hypothermic irrigation solution decreased temperature irrigation solution phacoemulsification cataract surgery corneal edema corneal damage central corneal thickness endothelial cell loss post-operative inflammation
Conditions
Interventions
In the standard treatment of phacoemulsification, we normally use room temperature irrigation solution.,we use the decreased temperature irrigation solution in phacoemulsification to study its effect
room temperature irrigation solution,10 degree celcius irrigation solution ,4 degree celcius irrigation solution
Sponsors
Research funds, Faculty of medicine, Khon Kaen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. patients of out patient unit, ophthalmology department, Srinagarind Hospital who are diagnosed nuclear cataract grade 2-3 according to WHO/PBD cataract grading 2. age between 18-80 years old
Exclusion criteria
Exclusion criteria: 1. those who has already been a participant of the study for another eye 2. those who has been diagnosed any of these following conditions in the eye that plan for the surgery ; glaucoma, shallow anterior chamber, pseudoexfoliation syndrome, any ocular diseases that have effect on endothelial cells, uveitis, previous intraocular surgery, pterygium that involve area of central corneal thickness or scar of pteryium excision that involve area of central corneal thickness, previous ocular trauma, infection, autoimmune disease, other ocular disease, currently on any ocular medications. 3. those whose endothelial cell counts are less than 1500 cells per squaremillimeter 4. those whose central corneal thickness is more than 600 micrometer 5. those who is diagnosed severe dry eye grade 3-4 according to DEWS definition and classification 6. those who is diagnosed complicated cataract.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean central corneal thickness post operation 1 day anterior segment optical coherence tomography | — |
Secondary
| Measure | Time frame |
|---|---|
| mean central corneal thickness post operation day 7 anterior segment optical coherence tomography,mean central corneal thickness post operative day 30 anterior segment optical coherence tomography,endothelial cell density loss post operative day 7 corneal confocal microscopy,endothelial cell density losss post operation day 30 corneal confocal microscopy,anterior chamber inflammation post operation day 1 Slit lamp examination,anterior chamber inflammation post operation day 7 slit lamp examination,anterior chamber inflammation post operation day 30 slit lamp examination,visual acuity post operative day1 snellen chart,visual acuity post operative day 7 snellen chart,visual acuity post operation day 30 snellen chart | — |
Countries
Thailand
Contacts
Public ContactPitchapa Srisuriyajan
Faculty of medicine, Khon Kaen university
Outcome results
None listed