The patient 18 years and older ,The patients diagnosed with primary hypereosinophilia leukocyte count more than 1,500 per microliter for a period of more than 1 month. Incidence of genetic abnormalities in patients with primary hypereosinophilia.
Conditions
Interventions
The patient 18 years and older ,The patients diagnosed with primary hypereosinophilia leukocyte count more than 1,500 per microliter for a period of more than 1 month in field of hamatology .
Diagnostic
he patient 18 years and older ,The patients diagnosed with primary hypereosinophilia .
Sponsors
Siriraj Hospital Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) The patients diagnosed with primary hypereosinophilia type white blood cells greater than 1,500 per microliter for a period of more than 1 month 2) 18 years of age and over 3) Patients who received the gene test The specific targeted fusion gene panel with hypereosinophilia 4) was welcomed to join the program by signing.
Exclusion criteria
Exclusion criteria: 1.The patient was detected from a bacterial infection by antibody detection Research projects in which patients are examined. Incidence of nasopharyngeal carcinoma in patients primary hypereosinophilias 686 / 2563 (IRB2) 2.Patients with allergic history 3.Asthma patients 4. Patients with immune diseases 5 Patients diagnosed with various cancers are not in peacetime. 6. History of steroid use in patients with herbs or drugs in the past three months 7. The patients had a history of adverse events leading to leukocyte disease, hypertension, and xa0; Penicillin, cephalosporin, GM-CSF, NSAID, ranitidine, isopropanol, isopropanol, alanine, amazillin sulfate, chlorazine, chlorazine Cyclospora
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mutations in hypereosinophilic patients first clinic visit Next generation sequencing for targeted gene mutations | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival 5 years From medical record (date of diagnosis, date of death, and date of last follow up) | — |
Countries
Thailand
Contacts
Public ContactWeerapat Owattanapanich
Division of Hematology,Faculty of Medicine Siriraj Hospital, Mahidol University .
Outcome results
None listed