Corneal Confocal Microscopy: A New Diagnostic tool for Neurofibromatosis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20210514002

Enrollment

Registered

2021-05-14

Start date

2021-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

compare the corneal nerve characteristics and inflammatory cells in patient with Neurofibromatosis type 1 and 2 Corneal Confocal Microscopy, Corneal Nerve, Neurofibromatosis

Interventions

healthy volunteers,Neurofibromatosis patients

Prevention,Prevention

control,case

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Patients who were diagnosed by a clinician with neurofibromatosis - Age 18-80 years old - Can cooperate with confocal microscopy and ocular examination

Exclusion criteria

Exclusion criteria: - Participants who have a corneal abrasion, ulcer, or active corneal infection - Participants who have ocular abnormalities that interrupt contact lens wear - Participants with previous corneal surgery - Participants who are allergic to topical ocular anesthesia

Design outcomes

Primary

Measure	Time frame
Inflammatory cells and corneal nerve density Visit 0 HRT-III confocal microscopy	—

Secondary

Measure	Time frame
Corneal nerve differentiation Visit 0 Compare corneal nerve density in between groups	—

Countries

Thailand

Contacts

Public ContactChareenun Chirapapaisan

Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University

chareenun@gmail.com024198037

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026