post sclerotherapy hyperpigmentation the complication of cosmetic sclerotherapy safety profile of using picosecond 1064 nm Nd:YAG laser in low-fluence non-ablative setting sclerotherapy hyperpigmentation laser sclerotherapy adverse effects
Conditions
Interventions
We use picosecond 1064 nm Nd:YAG laser to treat the post-sclerotherapy hyper pigmented areas. The skin will be prepared by 70% alcohol solution before the procedure. . The indicated setting and para
Experimental Device
Picosecond 1064 nm Nd:YAG laser
Sponsors
Institute of Dermatology, Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patient is diagnosed as post-sclerotherapy hyperpigmentation from sclerotherapy using 0.1- 1% polidocanol in liquid or foam solution. Off- treatment time is 3-months period. 2. No truncal reflux by Duplex ultrasound study. 3. The patient has 2 lesions or more. 4. Those lesions has similar melanin index. 5. Age > 18 years. 6. Fitzpatrick skin type III-V 7. Patient could make a visit as appointed 8. Patient has no history of using bleaching agents such as hydroquinone, retinoids prior to the study.
Exclusion criteria
Exclusion criteria: 1. Patient is receiving anticoagulant, minocycline or iron supplements. 2. Patient has received laser treatment on the study sites within 6 months. 3. Pregnant patient 4. Patient with history of photosensitive conditions 5. Patient with history or risk of keloidal scar formation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean melanin index at 4 weeks and 8 weeks after the intervention Mexameter | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfactory score 4 weeks after the intervention Patient reported outcome using a 5-point rating scale questionnaire.,Physician evaluation score 4 weeks after the intervention Physician reported outcome using a 5-point rating scale questionnaire. | — |
Countries
Thailand
Contacts
Public ContactTanongkiet Tienthavorn
Institute of Dermatology
Outcome results
None listed