The effectiveness of preoperative carbohydrate oral (CHO) loading on postoperative insulin resistance in laparotomy gynecological surgery compared with a fasting protocol

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20210503002

Enrollment

Registered

2021-05-03

Start date

2021-05-08

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effectiveness of preoperative carbohydrate oral (CHO) loading on postoperative insulin resistance in laparotomy gynecological surgery compared with a fasting protocol Fasting protocol means overnight fasting prior to operative day

Interventions

Carbohydrate oral loading (12.5 g/100 ml) 400 ml at 22.00 the day before surgery and 2 hr prior to surgery,Fasting overnight from the day before surgery

Experimental Dietary Supplement,No Intervention No treatment

CHO ,Fasting

Eligibility

Sex/Gender

Female

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patient who uudergoing laparotomy gynecological surgerey

Exclusion criteria

Exclusion criteria: Diabetic patient ASA class I-II Allergy to carbohydrate drink Hypoglycemia Pelvic inflammatory diseases Receiving immunosuppressive therapy

Design outcomes

Primary

Measure	Time frame
Insulin resistance 06.00 at day of surgery and 6 hr after surgery HOMA-IR	—

Secondary

Measure	Time frame
Inflammatory response 06.00 at day of surgery and 6 hr after surgery CRP, serum albumin,Unwellness 0-4,4-8,8-12,12-24 hr after surgery Visual analogue scale,Pain 0-4,4-8,8-12,12-24 hr after surgery Visual analogue scale	—

Countries

Thailand

Contacts

Public ContactChanprim Ratanasaenghirun

Phramongkutklao hospital

black_por@hotmail.com0866102090

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026