anti-mycobacterial induced optic neuropathy ethambutol toxic optic neuropathy isoniazid toxic optic neuropathy linezolid toxic optic neuropathy visual outcome severe visual impairment
Conditions
Interventions
Anti-mycobacterial induced optic neuropathy with severe visual impairment (VA 20/200 or worse),Anti-mycobacterial induced optic neuropathy without severe visual impairment (VA better than 20/200)
Prevention,Prevention
Anti-mycobacterial induced optic neuropathy with severe visual impairment,Anti-mycobacterial induced optic neuropathy without severe visual impairment
Sponsors
None listed
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patient who is diagnosed as anti-mycobacterial induced optic neuropathy including: 1. ethambutol optic neuropathy 2. isoniazid optic neuropathy 3. linezolid optic neuropathy During 10-year period retrospectively at King Chulalongkorn Memorial Hospital
Exclusion criteria
Exclusion criteria: The patient who has eye or neurological condition that affect the visual outcomes resemble to toxic optic neuropathy such as: 1. maculopathy of any causes 2. optic chiasmal disorders 3. optic neuritis 4. compressive optic neuropathy 5. hereditary optic neuropathy 6. nutritional optic neuropathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity Final follow-up Snellen chart and ETDRS chart | — |
Secondary
| Measure | Time frame |
|---|---|
| prevalence of visual impairment 10 years proportion | — |
Countries
Thailand
Contacts
Public ContactSupanut Apinyawasisuk
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed