Patients with chronic headache (by definition) known as migraine (according to the IHS diagnostic criteria) Aspirin Migraine Disorders Headache Vascular Malformations Brain
Conditions
Interventions
Propranolol 10 mg three times daily with Nortriptyline 25 mg once daily and Aspirin 81 mg daily ,Propranolol 10 mg three times daily with Nortriptyline 25 mg once daily and Aspirin 81 mg daily and Pla
Experimental Drug,Placebo Comparator Drug
Intervention group,Control group
Sponsors
Artesh University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with chronic headache (by definition) known as migraine (according to the IHS diagnostic criteria) Patients who have had brain lateral venous sinus stenosis in MRV according to a report by a radiologist and confirmed by a neurologist (Interventional Fellowship)
Exclusion criteria
Exclusion criteria: Patients with headache who did not meet the criteria for chronic headache Patients with MRV who have evidence in favor of other brain lesions such as tumors or vascular malformations Patients with a history of vascular disease or Brain space lesions Contraindications to aspirin use (aspirin allergy, history of peptic ulcer, history of asthma) The patient's unwillingness to cooperate or continue the plan Pregnancy, breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| severity of migraine Before the intervention, 1 months after the intervention Visual Analogue Pain Scale (VAS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of headache, duration of headache, number of headaches Before intervention, 1 months after intervention Visual Analogue Scale(VAS) | — |
Countries
Iran
Contacts
Public ContactMohammad Shafiee
General Practitioner, Artesh University of Medical Sciences
Outcome results
None listed