Dementia Bradycardia Dementia Cholinesterase inhibitor Bradycardia
Conditions
Interventions
Dementia patients who were treated with ChEIs ( Donepezil, Rivastigmine, Galantamine). We included single ChEIs all the study period or switching therapy while treatment period. ,Dementia patients who
Treatment,Treatment
Dementia patients with Cholinesterase inhibitor treatment ,Dementia patients without Cholinesterase inhibitor treatment
Sponsors
Geriatric medicine, medicine department, Ramathibodi hospital, Mahidol university
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Newly diagnosed dementia patients (Dementia in Alzheimer's disease, Vascular dementia, Dementia in other diseases classified elsewhere, Unspecified dementia) at OPD memory and OPD geriatric, Ramathibodi hospital between 01/01/2009 and 31/12/2019 2. Age at least 60 years or more 3. Existed at least 2 heart rate record from index date
Exclusion criteria
Exclusion criteria: 1. Pre-existing bradycardia ( second degree AV block Mobitz type II, third degree AV block, pacemaker implanted) patients 2. No index date of dementia diagnosis or referral patients from others hospital
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Repeated bradycardia until bradycardia was existed or death or loss follow up Heart rate less than 60 beat per minute 2 times | — |
Secondary
| Measure | Time frame |
|---|---|
| association factors of bradycardia in dementia patients until bradycardia was existed or death or loss follow up Heart rate less than 60 beat per minute 2 times | — |
Countries
Thailand
Contacts
Public ContactKochakorn Sawasdichai
Mahidol university
Outcome results
None listed