A Randomized Controlled Trial Comparing Chlorhexidine in Water and Povidone Iodine for Surgical Site Preparation in Abdominal Surgery

Different Skin Antisepsis Preparation: A Double-Blind Randomized Controlled Trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20210426003

Enrollment

340

Registered

2021-04-26

Start date

2020-08-03

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical site infection rate Chlorhexidine in water Povidone iodine Surgical Site Infection Abdominal Surgery

Interventions

Skin preparation with chlorhexidine in water before abdominal surgery,Skin preparation with povidone iodine before abdominal surgery

Experimental Drug,Experimental Drug

Chlorhexidine in water,Povidone iodine

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age > 18 years 2.Patients undergoing elective abdominal surgery 3.Open abdominal surgery as standard technique 4.Agree for informed consent

Exclusion criteria

Exclusion criteria: 1. Age > 75 years 2. Allergic to chlorhexidine and povidone iodine 3. Dirty wound classification or previous infection 4. Pregnant or breast feeding women 5. Reject to sign informed consent

Design outcomes

Primary

Measure	Time frame
Surgical site infection in 30 days in 30 days after intervention Surgical site infection event	—

Secondary

Measure	Time frame
Readmission rate at 30 days after intervention Readmission event	—

Countries

Thailand

Contacts

Public ContactThanaporn Nuangphuet

Faculty of Medicine, Ramathibodi Hospital

toyz123456thana@gmail.com0816990385

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026