Healthy volunteers with mild-to-moderate gingivitis. Gingivitis
Conditions
Interventions
Volunteers assigned to rinse thier mouth with indicated mouthwash for 1 minute, daily twice (12 h apart) for 14 days. Avoid eating or drinking for 15 minutes after using mouthwash.,Volunteers assigne
Placebo Comparator Other,Experimental Other,Experimental Other,Experimental Other,Active Comparator Other
Placebo mouthwash,KL mouthwash,KL + MO mouthwash,KL + NE mouthwash, 0.12% chlorhexidine (CHX) mouthwash
Sponsors
Research and Researchers for Industries (RRI)
Khaolaor Laboratories CO.,LTD
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. 18-60 years old, 2. diagnosed with mild-to-moderate gingivitis with gingival index (GI) and plaque index (PI) scores less than or equal to 2, 3. good general health, and 4. able to communicate in Thai fluently.
Exclusion criteria
Exclusion criteria: 1. wear orthodontic appliances or implants, 2. presence of periodontitis, 3. use of drugs including antibiotics, anti-inflammatory, anticoagulants, anticonvulsants, im-munosuppressants and chemotherapy drugs within the past six months, 4. patholo-gies of diabetes, xerostomia, oral cancer or receiving radiation therapy, 5. smoker, 6. pregnant or breastfeeding, 7. allergic to herbs or chemical constituents in mouthwash, 8. severe alcoholism, and 9. presence of mucous membrane pemphigoid.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival inflammation, Dental plaque At day 0 and day 15 of the intervention Gingival index score, Plaque index score | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of oral microorganisms At day 0 and day 15 of the intervention Spread plate method | — |
Countries
Thailand
Contacts
Public ContactKanchana Usuwanthim
Faculty of Allied Health Sciences, Naresuan University
Outcome results
None listed