Parkinson'
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Parkinson's disease without cognitive impairment: 1) Diagnosed with idiopathic PD by a neurologist, 2) Hoehn and Yahr stage I to III, 3) Receive regular medication for treating Parkinson's disease, e.g., Levodopa, 4) >3 months of stable anti-Parkinson's medication, 5) Walk 1 min independently without assistive device, 6) Correctly respond to visual and auditory information, 7) Mini-mental state examination (MMSE) >=24, and 8) 20-80 years old Parkinson's disease with cognitive impairment: same as above, as well as 9) Montreal Cognitive Assessment (MoCA) <26
Exclusion criteria
Exclusion criteria: All participants: 1) unstable health condition, and 2) any orthopedic, neurological, or psychological disease affecting participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain activity assess after enrollment functional near-infrared spectroscope (fNIRS),Obstacle-crossing performance assess after enrollment GaitRite system,Obstacle-crossing gait assess after enrollment Gait up | — |
Secondary
| Measure | Time frame |
|---|---|
| Global cognitive function assess after enrollment Montreal Cognitive Assessment,Executive function assess after enrollment Verbal Fluency Test,Attention assess after enrollment Digit Span Test,Visuospatial assess after enrollment Rey Osterrieth Complex Figure test,Usual walking performance assess after enrollment Gait up,Balance assess after enrollment Timed up and go,Motor symptom assess after enrollment Unified Parkinson's Disease Rating Scale-Part III,Falls risk assess after enrollment Falls Efficacy Scale International,Quality of life assess after enrollment Parkinson's disease questionnaire-39 item | — |
Countries
Taiwan
Contacts
Department of Physical therapy and Assistive Technology, National Yang Ming Chiao Tung University