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The brain activity and motor performance during obstacle-crossing gait and effects of motor and cognition complex training - Study of Parkinson's disease with or without mild cognitive impairment (Part I)

The brain activity and motor performance during obstacle-crossing gait and effects of motor and cognition complex training - Study of Parkinson's disease with or without mild cognitive impairment (Part I)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20210420001
Enrollment
60
Registered
2021-04-20
Start date
2021-03-18
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson&#039

Interventions

Parkinson&amp
#039
s disease without cognitive impairment,Parkinson&amp
s disease with cognitive impairment,Healthy elderly with normal cognition
Screening,Screening,Screening
s Disease - normal cognition,Parkinson&amp
s Disease - mild cognitive impairment,Healthy elderly

Sponsors

National Yang Ming Chiao Tung University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Parkinson's disease without cognitive impairment: 1) Diagnosed with idiopathic PD by a neurologist, 2) Hoehn and Yahr stage I to III, 3) Receive regular medication for treating Parkinson's disease, e.g., Levodopa, 4) >3 months of stable anti-Parkinson's medication, 5) Walk 1 min independently without assistive device, 6) Correctly respond to visual and auditory information, 7) Mini-mental state examination (MMSE) >=24, and 8) 20-80 years old Parkinson's disease with cognitive impairment: same as above, as well as 9) Montreal Cognitive Assessment (MoCA) <26 Healthy elderly: 1) Walk 1 min independently without assistive device, 2) Mini-mental state examination (MMSE) >=24

Exclusion criteria

Exclusion criteria: All participants: 1) unstable health condition, and 2) any orthopedic, neurological, or psychological disease affecting participation

Design outcomes

Primary

MeasureTime frame
Brain activity assess after enrollment functional near-infrared spectroscope (fNIRS),Obstacle-crossing performance assess after enrollment GaitRite system,Obstacle-crossing gait assess after enrollment Gait up

Secondary

MeasureTime frame
Global cognitive function assess after enrollment Montreal Cognitive Assessment,Executive function assess after enrollment Verbal Fluency Test,Attention assess after enrollment Digit Span Test,Visuospatial assess after enrollment Rey Osterrieth Complex Figure test,Usual walking performance assess after enrollment Gait up,Balance assess after enrollment Timed up and go,Motor symptom assess after enrollment Unified Parkinson's Disease Rating Scale-Part III,Falls risk assess after enrollment Falls Efficacy Scale International

Countries

Taiwan

Contacts

Public ContactRay Yau Wang

Department of Physical therapy and Assistive Technology, National Yang Ming Chiao Tung University

rywang@ym.edu.tw886228267210

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026