stable chronic obstructive pulmonary disease chronic obstructive pulmonary disease diaphragm parasternal muscle ultrasound
Conditions
Interventions
Patients with stable modorate to severe COPD (according to GOLD classification) will be performed parasternal muscles and diaphragm ultrasounds,Healthy volunteer ill be performed parasternal muscles a
Diagnostic,Diagnostic
Stable COPD ,Heatlhy volunteer
Sponsors
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: COPD group 1. Age >/= 40 years 2. Diagnosed COPD according to GOLD criteria (post-bronchodilator FEV1/FVC < 0.70) 3. Post-bronchodilator FEV1 35-79 %predicted within the past 6 months Control group 1. Age >/= 40 years 2. Normal spirometry (FEV1/FVC >/= 0.70 and FVC >/= 80 %predicted)
Exclusion criteria
Exclusion criteria: COPD group 1. History of acute exacerbation of COPD within the past 3 months 2. History of thoracic surgery 3. Diagnosed diaphragm paralysis or chronic neuromuscular disease 4. Pregnant woman 5. Refuse to participate Control group 1. History of thoracic surgery 2. Other respiratory diseases such as pneumothorax, pleural effusion, or pulmonary fibrosis 3. Pregnant woman 4. Refuse to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thickness of parasternal muscle 5 minutes Ultrasound | — |
Secondary
| Measure | Time frame |
|---|---|
| Thickening fraction of parasternal muscle 5 mntues Ultrasound,Thickening fraction of diaphragm 5 minutes Ultrasound,Correlation between thickening fraction of parasternal muscle and diaphragm with severity of COPD 5 minutes Ultrasound | — |
Countries
Thailand
Contacts
Public ContactNuttapol Rittayamai
Department of Medicine, Faculty of Medicine Siriraj Hospital
Outcome results
None listed