Post operative pain in multiple level spine surgery (Decompressive laminectomy + Instrumentation + Posterolateral fusion) for degenerative spine patients spine surgery Dexamethasone reduce post operative pain
Conditions
Interventions
- Perioperative intravenous dexamethasone injection at 30 minutes before surgery in-patient department.
- Dose 0.15 mg/Kg with bolus dose , up to 50 ml by normal saline solution ,- Perioperative intr
intravenous dexamethasone group,control group
Sponsors
Orthopedics department of Khon kaen Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Lumbar stenosis between L2-S1 level in Degenerative Group. Diagnosis by 1. History of radiculopathic pain , muscle weakness , Back pain with Failed conservative Treatment or Progressive neuro deficit 2. Physical examination were detected weakness of key motor muscle and decrease sensation test (dermatome) 3. MRI LS spine was detected Stenosis of Lumbar spine level
Exclusion criteria
Exclusion criteria: 1.Tuberculosis/Bacterial Spine infection , Trauma and spine metastasis 2.Patient with upper Gastrointestinal bleeding 3. Renal insufficiency (GFR < 30 ml/min/1.73m2) , Liver cirrhosis 4. Poor controlled Diabetes mellitus 5. allergic to Glucocorticoids drug 6. intake some Glucocorticoids drug (IV ,IM , Oral) in 1 month before surgery 7. Recent systemic infection 8. Refuse to participate in research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score at 48 hours after end of surgery pain score picture | — |
Secondary
| Measure | Time frame |
|---|---|
| total morphine consumption 0-48 hours after end of surgery total dose of morphine(mg)/Body weight(Kg) | — |
Countries
Thailand
Contacts
Public ContactTraitot Warasit
Khon kaen hospital
Outcome results
None listed