Hypoalbuminemia in peritoneal dialysis-related peritonitis Protein supplement Peritoneal dialysis Peritonitis Hypoalbuminemia
Conditions
Interventions
Whey protein supplement (Fresubin)
30 g per day, taken orally, for 30 days during active peritonitis
PLUS standard dietary counseling for PD-related peritonitis, Standard dietary counseling for PD-re
Experimental Dietary Supplement,No Intervention No treatment
Protein supplement,No protein supplement
Sponsors
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adult ESKD patients with PD-related peritonitis 2. Hypoalbuminemia (serum albumin < 3.5 mg/dl)
Exclusion criteria
Exclusion criteria: - Patients requiring parenteral nutrition - Patients with relapsing, repeated or recurrent PD-related peritonitis - Patients with PD-related peritonitis due to fungus, mycobacteria, or secondary peritonitis - Septic patients requiring vasopressor therapy - Critically-ill or terminally-ill patients (including those with bedridden status) - End-stage liver disease (Child-Pugh-Turcott classification B or C) - Active cancer - Pregnant women - Known allergy to whey protein
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite outcome of peritonitis-related death, relapsing peritonitis, and repeated peritonitis 3 months after completion of intervention Time to PD-related death, relapsing peritonitis or repeated peritonitis | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum albumin change from baseline 0, 1, 2, 3 months after completion of intervention Serum albumin change,Body weight change 0, 1, 2, 3 months after completion of intervention Body weight change | — |
Countries
Thailand
Contacts
Public ContactSurasak Faisatjatham
King Chulalongkorn Memorial Hospital
Outcome results
None listed