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Inhalational Ketamine compared to Entonox for moderate acute traumatic pain. A Randomized Controlled trial

Inhalational Ketamine compared to Entonox for moderate acute traumatic pain. A Randomized Controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210324007
Enrollment
42
Registered
2021-03-24
Start date
2019-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moderate traumatic pain inhaled ketamine entonox trauma

Interventions

inhalation entonox as a normal standard method of pain relief for trauma in the emergency method of delivery is via inhalation via facemask time duration 30 minutes content is oxygen 50 percent and n
Active Comparator Drug,Experimental Drug
Entonox,Ketamine

Sponsors

Secretariat of Research and Innovation Faculty of Medicine UKM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults, age more than 18 Moderate acute traumatic pain (40mm score to0mm VAS)

Exclusion criteria

Exclusion criteria: GCS 100kg, 180/100 Patients with head injury complaining of loss of consciousness, dizziness, vomiting/nausea (excluded despite evidence that ketamine does not exacerbate intracranial haemorrhage) Hemodynamically instable. History of recreational drug abuse History of significant heart, hepatic, lung, epilepsy condition. Other contraindication to Entonox Maxillofacial injuries Artificial, traumatic or spontaneous pneumothorax Air embolism Middle ear occlusion, ear infection. Decompression sickness Following a recent underwater dive Abdominal distention/ intestinal obstruction. Other contraindication to ketamine Increase intraocular pressure

Design outcomes

Primary

MeasureTime frame
pain reduction in 30 minutes 30 minutes pain score

Secondary

MeasureTime frame
time to meaningful pain reduction start from 0 minutes pain score

Countries

Malaysia

Contacts

Public Contactnik azlan nik muhamad

UKM

nikazlanmuhamad@hotmail.com006039145 5555

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026