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Comparison of postoperative analgesia between perineural dexmedetomidine and intravenous dexmedetomidine in axillary brachial plexus block : A randomized controlled trial

Comparison of postoperative analgesia between perineural dexmedetomidine and intravenous dexmedetomidine in axillary brachial plexus block : A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210317007
Enrollment
70
Registered
2021-03-17
Start date
2021-03-26
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patient undergoing forearm, wrist and hand surgery Axillary brachial plexus block, forearm, wrist and hand surgery, Dexmedetomidine

Interventions

Compare the effect of perineural dexmedetomidine and intravenous dexmedetomidine in axillary brachial plexus block on Duration of postoperative analgesia. Added Dexmedetomidine 100 mcg with local an
Active Comparator Drug,Active Comparator Drug
perineural dexmedetomidine added to local anesthetics in axillary brachial plexus block ,intravenous dexmedetomidine

Sponsors

Faculty of medicine, Ramathibodi hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patient undergo upper extremity opertion under axillry brachial plexus block 2. ASA PS 1-3 3. BMI 18-30 4.Patients agree to admit in the study with informed consent

Exclusion criteria

Exclusion criteria: 1.Neuropathy at upper extremity 2.Infection at axillary area 3. Allergic to local anesthetics 4. second or third degree AV block 5. Liver and renal disease 6. poor controlled systemic diseases 7.Uncooperated patient 8.Patient declined

Design outcomes

Primary

MeasureTime frame
Duration of analgesia Day 1,2 Duration since Block finish until patient starting pain

Secondary

MeasureTime frame
Duration of motor block Day1,2 Duration since Block finish until patient can move finger,Duration of sensory block Day1,2 Duration since Block finish until patient can feel the sensation,Onset of block 5,10,15,20,25,30 min after block Sensory and motor test,Success rate within 30 min after block can undergo surgery,Side effect of Dexmedetomidine 5,10,15,20,25,30 min after drug administered Blood pressure, HR

Countries

Thailand

Contacts

Public ContactAmornrat Tangjitbampenbun

Feculty o Medicine,Ramathobodi hospital

mae_ra131@hotmail.com0818756593

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026