intubated mechanical ventilated weaning diaphragm workload successful extubation prediction diaphragm thickness fraction diaphragm excursion peak contraction velocity peak relaxation velocity velocity-time integral TDI-derived maximal relaxation rate intubated mechanical ventilated weaning diaphragm workload successful extubation prediction diaphragm thickness fraction diaphragm excursion peak contraction velocity peak relaxation velocity velocity-time integral TDI-derived maximal rel
Conditions
Interventions
patients will record parameters before and after spontaneous breathing trial with automatic tube compensation (tube compensation 100%, PEEP 5cmH2O) for 30 minutes then record parameters before and aft
Active Comparator Device,Active Comparator Device
ATC then PSV,PSV then ATC
Sponsors
Self-funded
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: admitted to ICU in Ramathibodi hospital intubated and mechanically ventilated more than 48 hours passed to spontaneous breathing trial
Exclusion criteria
Exclusion criteria: Contra-indicated for diaphragm ultrasound Diaphragm pathology Diagnosed neuromuscular pathology e.g. MG, ALS Pregnancy Inability to participate until the end of the trial Withdrawal of informed consent The incomplete data collection form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| difference of diaphragm workload between ATC and PSV 30 minutes diaphragm thickness fraction | — |
Secondary
| Measure | Time frame |
|---|---|
| successful extubation prediction 2 hours diaphragm thickness fraction, diaphragm excursion, peak contraction velocity, peak relaxation velocity, velocity-time integral, TDI-derived maximal relaxation rate | — |
Countries
Thailand
Contacts
Public ContactNutarpa Kulkanokwan
Ramathibodi Hospital
Outcome results
None listed