insulin resistance in patients with subclinical hypothyroidism insulin resistance in patients with subclinical hypothyroidism
Conditions
Interventions
subclinical hypothyroidism female evaluate for insulin resistance,healthy volunteer females matched for age
Diagnostic,Diagnostic
subclinical hypothyroidism female,healthy females
Sponsors
alazhar university hospital at new deiitta
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: female patient age more than 18 years old, TSH level more than 5 mIU/l, free T4 and free T3 concentrations within the normal range
Exclusion criteria
Exclusion criteria: DM, Other endocrine diseases Drugs example(Insulin sensitizers, Contraceptive pills, Corticosteroid). Pregnancy. Sever co morbid diseases.as renal. liver and heart failure Patient aready on thyroxine treatment Patient with chronic HCV
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| normalization of TSH 3 months after end of intervention TSH by laboratory investigation | — |
Secondary
| Measure | Time frame |
|---|---|
| normalization of insulin resistance 3 months after end of intervention HOMA IR by laboratory investigation | — |
Countries
Egypt
Contacts
Public Contactkhaled elfayoumy
alazhar university
Outcome results
None listed