Skin wrinkles and roughness on face Oral of collagen, Topical application of collagen, Collagen cosmetic
Conditions
Interventions
pure collagen dipeptide from Tilapia 5 g./sachets that imported from japan, and have base cream collagen as a placebo,hydrolyze collagen from starfish 10% and base cream, and have oral administation
Oral administation collagen ,Topical application collagen
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
36 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Not menopause 2. Sign in to the consent form to participate in the study 3. No history of allergy to fish food 4. Not a skin disease or Allergic rash at the area to be tested 5. There are no contraindications or restrictions on the intake of protein as indicated by the doctor. 6. Do not take other protein supplements or drugs that can affect the skin condition, such as roaccutane, tranxenamic acid, d-penicillamine. During the trial 7. Not received any treatment for the face including Dermabrasion, Iontophoresis, radiofrequency (RF) in a period of 1 month prior to participation. 8. Not received Botulinum toxin injection at the site to be tested within 8 months prior to participation. 9. Not received filler in the area to be tested within 1 year prior to participating 10. Not smoking 11. Lifestyle do not exposed to heat and sunlight for many hours without protection 12. Not pregnant or breastfeeding
Exclusion criteria
Exclusion criteria: 1. Want to leave research or have reasons to leave research 2. Pregnant during the study 3. Experiencing side effects or allergic reactions During the research 4. Forget to take collagen from 3 sachets per 4 weeks 5. More than 5 grams of skin product left per 4 weeks 6. Received any treatment for the face including injected with Botulinum toxin, Filler, laser during the research 7. There was a change in skin care and health behavior from the original during research 8. Appearance severe allergic rashes in the examination area
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin wrinkles and roughness at week 0 before experimental and week 4,8 after end of the intervention(VisioscanVC98) and at week 4,8 after end of the intervention(SQ), (SEQ)and Photograph Medical devices (VisioscanVC98), Satisfaction questionnaire(SQ), Side effects questionnaire(SEQ) and Photograph (iphone11) | — |
Secondary
| Measure | Time frame |
|---|---|
| elasticity, moisture, water loss of the skin layers, evaluate side effects of using oral and topical collagen at week 0 before experimental and week 4,8 after end of the intervention(Cutometer dual MPA580 : Cutometer, Corneometer, TEWA) and at week 4,8 after end of the intervention(SQ), (SEQ)and Photograph Medical devices (Cutometer dual MPA580 : Cutometer, Corneometer, TEWA), Satisfaction questionnaire(SQ), Side effects questionnaire(SEQ) and Photograph (iphone11) | — |
Countries
Thailand
Contacts
Public ContactLeelawadee Pongkunakorn
Department of Science Program in Anti-Aging and Regenerative Medicine Integrative Medicine College Dhurakij Pundit University
Outcome results
None listed