Early stage cervical cancer (stage IA2-IIA) Early stage cervical cancer, sentinel lymph node, ultastaging
Conditions
Interventions
1.Patient was lithotomy., 2.Laparoscopy or Laparotomy approach to peritoneal cavity.,3.Indocyanine green : powder 25 mg mixed sterile water for injection 20 ml (1.25 mg/ml) injected in cervical at 3,6
clock. ,4. Waiting about 10 minutes during opened bilateral retroperitoneal spaces. ,5. Near infrared fluorescence was used to detection sentinel LN. ,6. Sentinel LN were detected and biopsy.,7. Both
Experimental Procedure/Surgery
SLN mapping and ultrastaging
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Early stage cervical cancer (stage IA2-IIA) patients, who detect cervical cancer lesion size less than 4 cm underwent surgery in Siriraj hospital. 2.The surgical process are include open laparotomy and laparoscopic surgery. 3.No previous treatment (radiotherapy, chemotherapy) 4.No underwent pelvic and paraaortic Lymph node Surgery. 5.No contraindication for indocyanine green (iodine sensitivity , hepatic impairment)
Exclusion criteria
Exclusion criteria: 1.Patient can't be able to underwent SLN surgery., 2. pregnancy women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate of sentinel LN 2 years Frozen section and ultrastaging | — |
Secondary
| Measure | Time frame |
|---|---|
| Compared Sentinel LN dectection rate between Frozen section and ultrastaging , False negative rate, sensitivity, evaluation factors 2 years Frozen section and ultrastaging | — |
Countries
Thailand
Contacts
Public ContactPichamon Pitakpaiboonkul
Gynecologic oncology,Siriraj Hospital, Mahidol University
Outcome results
None listed