hypertension ACEI ARB Hypotensionj
Conditions
Interventions
one-quarter dose of ACEI/ARB on the morning of surgery,full dose of ACEI/ARB on the morning of surgery
Experimental Drug,Experimental Drug
Sponsors
Department of Anesthesiology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: adult patients older than 18 years, ASA physical status II to III, receiving ACEI or ARB for hypertension at least 3 months, who were undergoing elective non cardiac surgery under general anesthesia with endotracheal intubation by direct laryngoscopy.
Exclusion criteria
Exclusion criteria: Exclusion included patients who took ACEI/ARB only in the evening, patients who concomitant used of ACEI and ARB, patients with poorly controlled hypertension and patients who have history of end-organ damage such as stroke, myocardial infarction, congestive heart failure, and renal insufficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of hypertension one hour after general anesthesia blood pressure in mmHg | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of hypertension preinduction and after induction blood pressure in mmHg | — |
Countries
Thailand
Contacts
Public ContactWorapot Apinyachon
Faculty of medicaine Ramathibodi Hospital Mahidol University
Outcome results
None listed