Performance of low risk criteria in the evaluation of direct oral challenge for children with beta-lactam allergy (multicenter study)

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20210225004

Enrollment

400

Registered

2021-02-25

Start date

2021-02-05

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the patients with low-risk betalactam allergy betalactam allergy

Interventions

direct oral challenge test

Experimental Drug

betalactam allergy

Eligibility

Sex/Gender

All

Age

5 Years to 18 Years

Inclusion criteria

Inclusion criteria: children aged 5-18 years old with history of low-risk betalactam allergy

Exclusion criteria

Exclusion criteria: high-risk of betalactam allergy immunocompromised uncontrolled cardiac/pulmonary disease

Design outcomes

Primary

Measure	Time frame
no reaction after drug challenge after continue drug challenge for 5 days negative test	—

Secondary

Measure	Time frame
protocol publication for non-allergist within 1 yr of the end of study accuracy of protocol	—

Countries

Thailand

Contacts

Public Contactchayaniss pachasidchai

Faculty of Medicine Ramathibodi Hospital Mahidol University

mnanmua_6@hotmail.com66846464981

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026