Healthy woman Pycnogenol Coenzyme Q10 Skin elasticity Skin hydration Melanin index
Conditions
Interventions
The intervention group participants will receive 40 mg French Maritime Pine Bark Extract twice daily plus 30 mg Coenzyme Q10 supplement daily for 8 weeks,The placebo group participants will receive
Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement
French Maritime Pine Bark Extract and Coenzyme Q10,French Maritime Pine Bark Extract
Sponsors
Pharma Nord S.E.A Co.,Ltd
Eligibility
Sex/Gender
Female
Age
35 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Female volunteers 2. Age 35-45 3. No medical condition, no serious disease or chronic disease those may effect the research 4. Not a menopause 5. Willingness for the study and sign in consent form 6. No history of French Maritime Pine bark extract or Coenzyme Q10 allergy 7. No skin disease, Eczema around the test area 8. Those who had not received an operative facial treatment, such as dermabrasion , Iontophoresis , Radiofrequency within 1 month prior to the research 9. Those who are not taking vitamins supplement, other antioxidants that have the effect of reducing wrinkles or increase skin moisture within 3 months before participating in the research 10. Those who had not received the BOTOX injection around the area to be tested within 8 months prior to the research 11. Those who had not received a Filler injection around the area to be tested within 1 year prior to the research 12. Non smoker or those who do not have regular exposure to sunlight without sunscreen protection 13. No pregnancy and lactation .
Exclusion criteria
Exclusion criteria: 1. Those who need to leave the research 2. Get pregnant during the research 3. Forget to take the tested products more than 1 time a week with follow-up by calling or by LINE application 4. Get BOTOX , FILLER , STEM CELL injection or Laser treatment during the research 5. Change in vitamin or supplement intake habits such as take more than usual or stop taking what they take regularly 6. Allergic to any ingredient of the tested products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin elasticity at 6 and 8 weeks Cutometer,Skin hydration at 6 and 8 weeks TEWAmeter, Corneometer | — |
Secondary
| Measure | Time frame |
|---|---|
| Pigmentation at 6 and 8 weeks Mexameter | — |
Countries
Thailand
Contacts
Public ContactKamolluck Anannithiwut
College of Integrative Medicine, Dhurakij Pundit University
Outcome results
None listed