Patellofemoral Arthritis Patellofemoral arthritis Chondromalacia patella Anterior knee pain Hyaluronic acid Intra-articular injection
Conditions
Interventions
intra-articular injection of 3 ml of intermediate molecular weight hyaluronic acid ,intra-articular injection of 3 ml of physiologic buffered saline
Active Comparator Drug,Placebo Comparator Drug
Intra-articular hyaluronic acid,Physiologic buffered saline solution
Sponsors
Queen Savang Vaddhana Memorial Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of Patellofemoral osteoarthritis with anterior knee or retropatellar pain that is exacerbated by knee-bending activity including joint-loading activities, going up the stairs, or standing up from sitting position 2. Age 20-60 years 3. Pain score according to Visual Analogue Scale (VAS) more than equal to 3 4. a trial of conservative treatment for 3 months with no significant improvement 5. Radiological diagnosis of Iwano Classification grade 1-4
Exclusion criteria
Exclusion criteria: 1. Osteoarthritis of tibiofemoral joint according to Kellegren and Lawrence Classification of at least grade 3 2. History of allergic reaction of any medication in this study 3. History of prior injury to the knee 4. Infection at the knee
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain 2, 4, 8, 24 week VAS score | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional score 2, 4, 8, 24 week WOMAC Score,Range of motion 2, 4, 8, 24 week Knee flexion and Extension in degrees,Adverse reaction 2, 4, 8, 24 week Clinical Observation of skin reaction and infection | — |
Countries
Thailand
Contacts
Public ContactPanyajarn Laohapornsvan
Queen Savang Vadhanna Memorial Hospital
Outcome results
None listed