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Effect of Astaxanthin, Natural plant-based oil, Vitamin E and Vitamin D3 on oxidative stress in overweight and obese women

Effect of Astaxanthin, Natural plant-based oil, Vitamin E and Vitamin D3 on oxidative stress in overweight and obese women: A randomized double blind, placebo-controlled clinical trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210220001
Enrollment
38
Registered
2021-02-20
Start date
2021-03-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy women Astaxanthin Oxidative stress Obeses Overweight MDA Malondialdehyde Ox-LDL

Interventions

Take 2 softgels oral after breakfast for 8 weeks Ingredient per softgel Flaxseed oil 139.4 mg, Borage oil 132 mg, Haematococcus pluvialis Oleoresin 50 mg as Astaxanthin 5 mg, Perilla oil 43 mg, Avoca
Experimental Dietary Supplement,Placebo Comparator No treatment
Astaxanthin,MCT oil

Sponsors

Prevent U Company Limited
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Female 2. Aged 35-45 years old 3. BMI 23-29.9 kg/M2 4. General good health and mental condition 5. No evidence of underlying disease 6. Currently having regular menstrual cycles 7. Pregnancy or current lactation 8. No history of Carotenoids allergy 9. No taking of dietary supplement within 2 weeks prior to the study 10. Non smoker

Exclusion criteria

Exclusion criteria: 1. Inability or unwillingness to participate in the study or sign the informed consent form 2. Adverse event occurred during study 3. Current pregnancy 4. Forget to take the test products continued for two days or more than two days per week or more than four days per month 5. Intentional lose weight or lifestyle modification 6. Current personal diagnosis of depression

Design outcomes

Primary

MeasureTime frame
Oxidative stress at 8 weeks after end of intervention Malondialdehyde,Oxidative stress at 8 weeks after end of intervention Oxidized low density lipoprotein

Secondary

MeasureTime frame
Safety at 8 weeks after end of intervention Blood urea nitrogen,Safety at 8 weeks after end of intervention Creatinine,Safety at 8 weeks after end of intervention Aspartate aminotransferase,Safety at 8 weeks after end of intervention Alanine aminotransferase

Countries

Thailand

Contacts

Public ContactThanatporn Thamwisutthiwarakorn

Dhurakit Pundit University

devil_walnut@hotmail.com0869000606

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026