Pediatric with acute lymphoblastic leukemia Pediatrics Acute lymphoblastic leukemia BMI remission outcomes
Conditions
Interventions
BMI for age z score is less than minus two,BMI-for-age Z score is between minus two and plus two,Overweight and obesity are BMI-for-age Z score are more than plus two
underweight patient,Normal weight patient,Overweight and obesity patient
Sponsors
Piyathida Wongmast
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Inclusion criteria
Inclusion criteria: Newly diagnosed 0-18 yr childhood acute lymphoblastic leukemia patients treated between 2014 and 2019 in 3 tertiary hospitals in Thailand, from Thai pediatric oncology group(TPOG) and treated with TPOG protocol.
Exclusion criteria
Exclusion criteria: At least one of the following; 1. Children younger than 2 years, normative BMI values unavailable 2. Incomplete medical record. 3. Previously other cancer. 4. Dead before induction chemotherapy. 5. Patients treated by individual protocol. 6. Known syndrome (e.g. Down) or Developmental disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| remission rate 4 weeks after start induction bone marrow examination | — |
Secondary
| Measure | Time frame |
|---|---|
| MRD at the end of induction 4 weeks after start induction chemotherapy flow cytometry,mortality outcomes 4 weeks after start induction chemotherapy number and percentage,adverse events during induction chemotherapy number and percentage,duration of induction timing between start induction chemotherapy until finish induction chemotherapy continuous data,time to ANC recovery timing between start induction chemotherapy until ANC recover more than 500 and 1,000 /microL continuous data,time to platelet recovery timing between start induction chemotherapy until platelet recover more than 50,000 and 100,000 /mm3 continuous data | — |
Countries
Thailand
Contacts
Public ContactPiyathida Wongmast
Khon Kaen university
Outcome results
None listed