Efficacy of Hyaluronic acid in improving outcome of spinal decompression

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20210211004

Enrollment

Registered

2021-02-11

Start date

2020-01-09

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar spinal stenosis in elderly patient Spinal stenosis, HA, Hyaluronic acid, Posterior decompression, Laminectomy

Interventions

Two vial of hyaluronic acid soaking in gelfoam apply to neural element after spinal decompression,Saline-soaked gelfoam apply on neural element after spinal decompression

Experimental Drug,Placebo Comparator No treatment

Hyaluronic acid,Normal Saline

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age more than 50 years. 2. Diagnosed with spinal stenosis. 3. Schedule for posterior decompression in ramathibodi hospital by Rama spine team

Exclusion criteria

Exclusion criteria: 1. Allergy to Hyaluronic acid. 2. Deny participation 3. Unable to communicate 4. Unable to follow up

Design outcomes

Primary

Measure	Time frame
Back pain 2, 6, 12, 18, 24 weeks Oswestry disability index,Quality of life 2, 6, 12, 18, 24 weeks EQ5D,Back pain 2, 6, 12, 18, 24 weeks VAS score of back pain,Leg pain 2, 6, 12, 18, 24 weeks VAS score for leg pain	—

Secondary

Measure	Time frame
Surgical site infection 24 weeks -	—

Countries

Thailand

Contacts

Public ContactChayapat Supachatwong

Ramarthibodi hospital

Chayapat.sup@gmail.com0858037209

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026