Effect of Two Difference Doses of Botulinum Toxin A on Infantile Esotropia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20210210001

Enrollment

Registered

2021-02-10

Start date

2021-05-02

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

strabismus that can make patient amblyopia have to surgery but there are many of complication from surgical technique and sedation technique so intraocular muscle botulinum toxin injection and solve this problem strabismus , botulinum toxin, infantile esotropia

Interventions

botulinum toxin A 5 U inject into medial rectus muscle under sedation by pediatric ophthalmologist specialist,botulinum toxin A 7.5 U inject into medial rectus muscle under sedation by pediatric opht

Active Comparator Drug,Active Comparator Drug

botulinum toxin A 5 U,botulinum toxin A 7.5 U

Eligibility

Sex/Gender

All

Age

1 Months to 15 Years

Inclusion criteria

Inclusion criteria: congenital esotropia age 40 diopter

Exclusion criteria

Exclusion criteria: previous history of strabismus surgery associated ocular disease such as ROP, amblyopia hypertropia > +4.00 D associated with other type of strabismus abnormal ocular movement abnormal neurodevelopment

Design outcomes

Primary

Measure	Time frame
prism diopter of esotorpia 1,3,6 month alternate prism cover test	—

Secondary

Measure	Time frame
compare complication of 2 doses of botulinum toxin A 1,3,6 month exotropia, ptosis, epiphora, dry eye	—

Countries

Thailand

Contacts

Public Contactpongpol kittiarnun

30000

Pongki@kku.ac.th0887228560

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026