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Quantitative cell free DNA from spent culture media at 48 and 54hours after Cleavage stage of embryo

Quantity of DNA in spent culture media in different duration exposed to embryo: prospective experimental study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20210209003
Enrollment
52
Registered
2021-02-09
Start date
2020-10-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility couple with indication for preimplantation genetic testing preimplantation genetic testing noninvasive spent culture media

Interventions

collect spent culture media at 54 hr after cleavage stage,collect spent culture media at 48 hr after cleavage stage
Experimental Other,No Intervention Other
spent culture media at 48 hr after cleavage stage,spent culture media at 54 hr after cleavage stage

Sponsors

Faculty of Medicine Ramathibodi hospital Mahidol university
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 45 Years

Inclusion criteria

Inclusion criteria: Female age between 30-45years old Infertility Indicated for PGT-A

Exclusion criteria

Exclusion criteria: Embryonic culture less than day 5 Embryonic grading less than early blastocyst stage (reference from Gardner and schoolcraft morphology classification,1999)

Design outcomes

Primary

MeasureTime frame
DNA quantity 12 months qPCR, Qubit—

Secondary

MeasureTime frame
Concordance of chromosome study result by spent culture media compare with trophectoderm biopsy 12 months trophectoderm biopsy—

Countries

Thailand

Contacts

Public ContactPornsri Niransuk

Mahidol University

tik.punnpunn@gmail.com0991461659

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026