Significant severe kyphoscoliosis Coagulopathy Allergy to local anesthetic agents Pneumothorax Intrathecal anesthesia Epidural anesthesia
Conditions
Interventions
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1 Patient undergoing elective video-assisted thoracoscopic surgery and open thoracotomy for lung surgery with American Society of Anesthesiologists Classification 1-3
Exclusion criteria
Exclusion criteria: 1 Inability to obtain informed consent 2 Patients who refuse to receive thoracic paravertebral block 3 Body mass index > 35 kg/m2 4 Pre-existing neuropathy (assessed by history and physical examination) 5 History of previous thoracic surgery 6 Significant thoracic kyphoscoliosis 7 Coagulopathy (platelets < 100,000/mL or INR > 1.4) 8 Allergy or contraindicated to medications used in study protocol (Bupivacaine, sevoflurane, propofol, cisatracurium, fentanyl, morphine 9 Chronic pain syndromes requiring opioid intake at home 10 Active infectious condition 11 Refuse to participate or withdraw their consent at any stage of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean pressure and waveform immediately during the procedure and 1 hour after surgery Pressure value in mmHg | — |
Secondary
| Measure | Time frame |
|---|---|
| Analgesia level at PACU within 1 hour after finishing operation Sensory loss assessed by dermatome levels | — |
Countries
Thailand
Contacts
Faculty of Medicine Ramathibodi Hospital