The return of gastrointestinal function and blood lactate between oxygen content guided goal-directed therapy and standard fluid therapy in major abdominal surgery patients Oxygen content Goal directed therapy Major abdominal surgery patients
Conditions
Interventions
SpOC guided group received protocol based on SpOC guided intravenous fluid, blood component, and oxygenation support to maintain SpOC more than 12 ml/dL and PVi less than17 %,In the Control group, the
Experimental Device,Experimental Device
Oxygen content guided GDT ,Standard fluid therapy
Sponsors
Maharaj Nakorn Chiang Mai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Age > 18 years old Elective open major abdominal surgery Estimated blood loss >500 ml Expected operative time >120 min
Exclusion criteria
Exclusion criteria: Patients refuse consent Gynecological surgery Trauma Septicemia Heart failure Cardiac arrhythmia Poor peripheral circulation Patient on pacemaker Aortic valvular disease Rapid high blood pressure from the vasoactive drug (Phenylephrine, Nicardipine) esCCI < 2.5 L/min/m2 Renal impairment (CKD 4, 5)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Return of gastrointestinal function Post operation daily Auscultation of bowel sound | — |
Secondary
| Measure | Time frame |
|---|---|
| Level of lactate Before and end of surgery Blood,Length of stay Post operation Day | — |
Countries
Thailand
Contacts
Public ContactSudthanom Kubpeng
Faculty of medicine, Chiang Mai university
Outcome results
None listed