Gynecologic cancer patient who received chemotherapy including pacllitaxel Gynecologic cancer Paclitaxel Chemotherapy-induced peripheral neuropathy
Conditions
Interventions
Cold therapy was performed using in-house developed velvet fabric bags with two pieces of 3M gel pack inside. The 3M gel pack was precooled in a freezing-compartment refrigerator before use. The velve
Experimental Procedure/Surgery,No Intervention No treatment
Cold therapy,Controlled
Sponsors
Siriraj Research Development Fund (Managed by Routine to Research: R2R)
Eligibility
Sex/Gender
Female
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: The gynecologic cancer patients who were 18 years-old or more and received chemotherapy including paclitaxel 175 mg/m2 every three weeks were included in this study .
Exclusion criteria
Exclusion criteria: Patients with preexisting subjective peripheral neuropathy symptoms before chemotherapy initiation, potential peripheral neuropathy due to prior chemotherapy regimen, including taxane or platinum, which had a recurrence of disease within one year, were not eligible in the study. The participants who had rheumatoid arthritis, diabetes mellitus, peripheral vascular disease, and using drugs treated for peripheral neuropathy symptoms were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chemotherapy-induced peripheral neuropathy after the chemotherapy course finished. FACT/GOG-Ntx score | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of CIPN after the chemotherapy course finished. FACT/GOG-Ntx | — |
Contacts
Public ContactTharinee Rahong
Obstetrics and Gynecology Department, Siriraj Hospital
Outcome results
None listed