patient 18-80 years admitted at Surin hospital which ST elevation myocardial infarction and percutaneous coronary intervention . Colchicine , ST elevation myocardial infarction , Percutaneous Coronary Intervention .
Conditions
Interventions
colchicine ( 0.6 mg) 1 tab oral per day for 30 days,placebo ( powder tablet) 1 tab oral per day for 30 days
Active Comparator Drug,Placebo Comparator Drug
Sponsors
surin hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: patients presented at Surin hospital with known case ST elevation myocardial infarction ( STEMI) and received percutaneous coronary intervention ( PCI).
Exclusion criteria
Exclusion criteria: 1.Pregnancy, 2.Breast feeding,3.active inflammation, 4. infectious disease, 5.current treatment of corticosteroids or other inflammatory agents, 6.hypersensitivity for colchicine, 7.chronic treatment of colchicine,8.chronic diarrhea, 9.colchicine intolerance or contraindication,10.severe renal failure, 11.hepatic failure ( Chid-Puge class B,C),12. cardiac arrest, 13.cardiogenic shock,14.heart failure NYHA class 3,4, 13. inability or unwilliness to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LV function at 3 months after end of the intervention echocardiography evalate LV function by modified bi plane | — |
Secondary
| Measure | Time frame |
|---|---|
| CRP at 1 months after end of the intervention Latex enhanced turbidi metrix immunoassay | — |
Countries
Thailand
Contacts
Public Contactthaworn choochunklin
surin hospital
Outcome results
None listed