Allergic rhinitis (AR) is one of the most common chronic diseases affecting 15-25% of worldwide children. In Thailand, an estimated AR prevalence is between 10 and 45%. AR is an inflammatory disorder of nasal mucosa marked by nasal congestion, rhinorrhea, and itching, often accompanied by sneezing and conjunctival inflammation. AR is recognized as a major chronic respiratory disease of children because of its high prevalence, detrimental effects on quality of life and school performance, and com
Conditions
Interventions
to use 5 ml with disposable syringes to irrigate each nostril twice a day for a period of 4 weeks,to use 5 ml with disposable syringes to irrigate each nostril twice a day for a period of 4 weeks
Experimental Drug,Active Comparator Drug
3% hypertonic saline nasal irrigation,Normal saline nasal irrigation
Sponsors
Bhumibol Adulyadej Hospital, Royal Thai Air Force
Eligibility
Sex/Gender
All
Age
6 Years to 15 Years
Inclusion criteria
Inclusion criteria: 1. age 6 to 15 years, 2. allergist diagnosed AR status with positive skin prick test, 3. total nasal symptom score greater than equal 4 at the first visit of this study
Exclusion criteria
Exclusion criteria: 1. nasal anatomic defects, 2. abnormal nasal ciliary function, 3. chronic respiratory tract infection, 4. ongoing allergen-specific immunotherapy 5. moderate-severe persistent asthma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nasal symptom 4 weeks Total nasal symptom score | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life 4 weeks Quality of life question | — |
Countries
Thailand
Contacts
Public ContactKittithat Rattanamaneewong
Bhumibol Adulyadej Hospital, Royal Thai Air Force
Outcome results
None listed