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Effects of Epidural Anesthesia on Postoperative Diaphragmatic Dysfunction Determined by Point-of-Care Ultrasound of the Diaphragm in Patients Undergoing Major Abdominal Surgery

Effects of Epidural Anesthesia on Postoperative Diaphragmatic Dysfunction Determined by Point-of-Care Ultrasound of the Diaphragm in Patients Undergoing Major Abdominal Surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Observational
Source
TCTR
Registry ID
TCTR20201226004
Enrollment
100
Registered
2020-12-26
Start date
2021-01-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major abdominal surgery Epidural analgesia Postoperative pulmonary complications Abdominal surgery Epidural analgesia Postoperative complications

Interventions

Continuous epidural anesthesia is performed before anesthetic induction with Touhy needle number 16G&#45
18G at thoracic or lumbar level. ,Patients dose not receive epidural block.
Supportive Care,Supportive Care
Epidural Group,Non&#45

Sponsors

Research Fund, Faculty of Medicine, Chiang Mai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age >18 years, ASA I-III, Elective major abdominal surgery

Exclusion criteria

Exclusion criteria: -Patients who refuse an informed consent for this research study -History of diaphragmatic abnormality such as diaphragmatic eventration or paralysis -History of phrenic nerve injury or palsy -History of neuromuscular disease -Cannot achieve correct diaphragm visualization -BMI ≥ 35 kg/m2 -Aortic aneurysm surgery -Preoperative intubation -Being planned for postoperative intubation by surgical/anesthesia team -Failure to extubate at the operating room -Patients with systemic infection or sepsis

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative diaphragm dysfunction within 48 hours after surgery Occurrence of the event

Secondary

MeasureTime frame
Incidence of postoperative pulmonary complications During admission (within 14 days) Occurrence of the event

Countries

Thailand

Contacts

Public ContactPrangmalee Leurcharusmee

Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University

prangmalee.l@cmu.ac.th053935522

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026