Health Condition= Participants who no have side effects from probiotic such as diarrhea,
Conditions
Interventions
Participants in placebo group received corn starch 10 mg/day during the 12 weeks of intervention. ,Participants in probiotic group received a probiotic L. paracasei HII01 50 × 109 CFU/day during
Placebo group,Probiotic group
Sponsors
Faculty of Pharmacy, Chiang Mai University
Faculty of Medicine,
Chiang Mai University
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Type 2 diabetic patients will be either sex (male or female) between the ages 20 to 70 years. 2) Patients who do not take antibiotic drugs for 14 days before starting of the study. 3) Patients who can listen, speak, write and read Thai language.
Exclusion criteria
Exclusion criteria: 1) Pregnant or nursing patients 2) Smokers 3) Patients with abnormal liver function test, ALT > 55 U/L, AST > 34 U/L, ALP > 125 U/L 4) Patients with abnormal renal function test, GFR ≤ 60 ml/min 5) Patients with history of malignant 6) Patients with micro and macro vascular complications 7) Patients with uncontrollable emotions which approved by the behavioral and cognitive test and physician 8) Patients with thyroid disorder or the endocrine metabolic disorders 9) Patients with chronic alcoholic or frequency ≥ 2 times/weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota composition change 12 weeks Real-Time PCR of feces bacteria in feces | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood biochemical that related with type 2 diabetes 12 weeks commercial colorimetric kit, commercial ELISA kit, | — |
Countries
Thailand
Contacts
Public ContactNarissara Lailerd
Faculty of Medicine, Chiang Mai University
Outcome results
None listed