Safety evaluation and effect of consumption of Isochrysis gabana and dill tea against oxidative stress in volunteers

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20201223004

Enrollment

Registered

2020-12-23

Start date

2021-02-16

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy conditions Isochrysis gabana Dill oxidative stress

Interventions

Subjects are received the placebo product which has same color and smell look like product of Isochrysis gabana and dill tea,Subjects are received product of Isochrysis gabana and dill tea 1,200 mg/

Placebo Comparator Dietary Supplement,Experimental Dietary Supplement,Experimental Dietary Supplement

Placebo,Isochrysis gabana and dill tea 1,200 mg/day,Isochrysis gabana and dill tea 2,400 mg/day

Eligibility

Sex/Gender

All

Age

40 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Aged between 40-65 years old 2.Body Mass Index (BMI) less than 25 kg/m2 3.Not vegetarian volunteers

Exclusion criteria

Exclusion criteria: 1.Volunteers who have serious physical illness such as cardiovascular diseases, respiratory diseases, neuropsychological diseases, head injury, diabetes mellitus, liver disease, cancer, autoimmune diseases and psychological disorder 2.Volunteers who require supplements or herbals within 2 months before participating in this study 3.Smoking more than 10 pieces/day 4.Alcohol addiction

Design outcomes

Primary

Measure	Time frame
Oxidative stress markers (MDA, CAT, SOD, GPx) 8 weeks Elisa method	—

Secondary

Measure	Time frame
The changes of hematological and clinical chemistry parameters 8 weeks laboratory,Phenolic compounds and Flavonoids 8 weeks laboratory,Homeostasis Model Assessment Insulin Resistance (HOMA-IR) and Insulin 8 weeks laboratory,Atherosclerosis index (AI), Atherogenic index of plasma (AIP) and Oxidized LDL 8 weeks laboratory,Stool examination (PH, Total lactic acid, Bifidobacterial, Short chain fatty acid) 8 weeks laboratory,Electrocardiogram 8 weeks electrocardiography equipment,Anxiety, depression and insomnia evaluation using questionnaire 8 weeks Questionair	—

Measure

Time frame

The changes of hematological and clinical chemistry parameters 8 weeks laboratory,Phenolic compounds and Flavonoids 8 weeks laboratory,Homeostasis Model Assessment Insulin Resistance (HOMA-IR) and Insulin 8 weeks laboratory,Atherosclerosis index (AI), Atherogenic index of plasma (AIP) and Oxidized LDL 8 weeks laboratory,Stool examination (PH, Total lactic acid, Bifidobacterial, Short chain fatty acid) 8 weeks laboratory,Electrocardiogram 8 weeks electrocardiography equipment,Anxiety, depression and insomnia evaluation using questionnaire 8 weeks Questionair

—

Countries

Thailand

Contacts

Public ContactWipawee Thukhammee

Khon Kaen University

wipath@kku.ac.th0850016805

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026