Skip to content

A randomized, non-inferiority trial of oral minoxidil 1.25 mg versus 5% topical minoxidil solution in the treatment of female pattern hair loss

A randomized, non-inferiority trial of oral minoxidil 1.25 mg versus 5% topical minoxidil solution in the treatment of female pattern hair loss

Status
Recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20201222005
Enrollment
44
Registered
2020-12-22
Start date
2021-07-16
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female pattern hair loss Female pattern hair loss oral minoxidil topical minoxidil

Interventions

oral minoxidil 1 mg per day for 48 weeks,5% topical minoxidil twice a day for 48 weeks
Experimental Drug,Active Comparator Drug
oral minoxidil 1 mg,5% topical minoxidil

Sponsors

Dermotology unit, King Chulalongkorn Memorial Hospital
Lead Sponsor
Dermotology unit&#44
Collaborator
King Chulalongkorn Memorial Hospital
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Female patients, aged 18-65 year who were diagnosed with female pattern hair loss 2. History, clinical and dermoscope showed Savin scale I-4, II-1 and II-2 3. No treatment before or stop previous treatment at least 3 months prior to study

Exclusion criteria

Exclusion criteria: 1. patients who have other co-morbidity diseases which effect to hair density such as any malignancy, anemia, hypothyroidism/hyperthyroidism, AIDS and autoimmune connective tissue disease and who have cardiovascular disease 2. patients who have other scalp disease ex. seborrheic dermatitis, scalp psoriasis, tinea capitis. 3. patients who have history of hair transplantation or have large scar on scalp 4. patients who have history of minoxidil allergy 5. pregnancy or lactation women 6. on Hormonal therapy or spironolactone

Design outcomes

Primary

MeasureTime frame
Change of terminal hair density at start, 12weeks, 24 weeks, 36 weeks and 48 weeks after start intervention Using Fotofinder Dermatoscope for evaluation of terminal hair density at midscalp

Secondary

MeasureTime frame
Change of total hair density at start, 12 weeks, 24 weeks, 36 weeks and 48 weeks after start intervention Using Fotofinder Dermatoscope for evaluation of total hair density at midscalp,Photographic assessment score at start, 24 weeks and 48 weeks after start intervention photographic assessment questionnaires,Satisfaction score at 24 weeks and 48 weeks after start intervention patient self-assessment questionnaires,Side effects at 4 weeks, 12 weeks, 24 weeks, 36 weeks and 48 weeks after start intervention questionnaires

Countries

Thailand

Contacts

Public ContactRatchathorn Panchaprateep

Faculty of Medicine, Chulalongkorn university

rpanchaprateep@gmail.com022564253

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026