changing of serum sodium after 24 hr intravenous fluid administration hypotonic solutions, isotonic solutions, hyponatremia, metabolic acidosis, children
Conditions
Interventions
Arm 2 receive hypotonic solution ,Arm 1 receive isotonic solution
Experimental Drug,Experimental Drug
Sponsors
Navamindradhiraj University
Eligibility
Sex/Gender
All
Age
3 Months to 5 Years
Inclusion criteria
Inclusion criteria: 1. Patients from 3 months to 5 years of age who admitted and require maintenance intravenous fluid solution 2. Initial serum sodium 130-140 mEq/L
Exclusion criteria
Exclusion criteria: 1. Patients with neurological disorders 2. Patients with congenital heart or acquired heart disease 3. Patients with hepatic disease 4. Patients with cancer 5. Patients with renal dysfunction 6. Patients with adrenal insufficiency 7. Patients with diabetes insidious 8. Patients with voluminous watery diarrhea 9. Patients with shock 10. Patients who had history of electrolyte imbalance 11. Patients who receive medication affect serum sodium e.g. diuretic
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study change in serum Na following the administration of hypotonic versus isotonic IVFS at 24 hour 24 hours after administration intravenous fluid serum sodium | — |
Secondary
| Measure | Time frame |
|---|---|
| To study Incidence of hyponatremia and hypernatremia 24 hours after administration intravenous fluid serum sodium,To study incidence of metabolic acidosis 24 hours after administration intravenous fluid serum HCO3, pH,To study change in serum Na following the administration of hypotonic versus isotonic IVFS at 48 hou 48 hours after administration intravenous fluid serum sodium | — |
Countries
Thailand
Contacts
Public ContactOrnatcha Sirimongkolchaiyakul
Navamindradhiraj University
Outcome results
None listed