Spine surgery is generally associated with intense pain in the postoperative period. In this period,
Conditions
Interventions
postoperative pain control with iv PCA morphine.,received ketamine 0.35mg/kg dilution with normal saline up to 10 ml. intravenous bolus before induction and continuous intravenous infusion 2.5mcg/kg/m
Control group,Intraoperative ketamine,Perioperative ketamine
Sponsors
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Anesthesiology department
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: elective spine surgery patient under GA age 18-75-year-old ASA physical status I-III
Exclusion criteria
Exclusion criteria: Pregnancy, psychiatric problems, chronic alcoholism, drug abuse, allergy to ketamine or morphine, history of receiving strong opioids before surgery, inability to use PCA, and lack of communication ability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphine consumption postoperative at 24 hour and at 48 hour milligram | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score at resting and movement 1, 6, 12, 24, 48 hour. Numeric of pain score,adverse effects of ketamine and morphine 1, 6, 12, 24, 48 hour. percentage | — |
Countries
Thailand
Contacts
Public ContactChusak Okascharoen
Ramathibodi Hospital Mahidol University
Outcome results
None listed