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A prospective, split-face, randomized study comparing fractional carbon dioxide laser with and without application of botulinum toxin A in the treatment of enlarged pores

A prospective, split-face, randomized study comparing fractional carbon dioxide laser with and without application of botulinum toxin A in the treatment of enlarged pores

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20201208008
Enrollment
22
Registered
2020-12-08
Start date
2020-12-08
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enlarged pores Enlarged pores treatment botulinum toxin Fractional carbondioxide laser

Interventions

Fractional carbondioxide laser&#44
then apply with 0.5 ml normal saline solution ,Fractional carbondioxide laser&#44
then apply with 10 units of botulinum toxin in 0.5 ml normal saline solution
Active Comparator Device,Experimental Other
Fractional carbondioxide laser with topical normal saline solution,Fractional carbondioxide laser with topical botulinum toxin

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor
Department of Dermatology&#44
Collaborator
Faculty of Medicine Siriraj Hospital&#44
Collaborator
Mahidol University
Collaborator

Eligibility

Sex/Gender
All
Age
25 Years to 40 Years

Inclusion criteria

Inclusion criteria: Enlarged pores

Exclusion criteria

Exclusion criteria: Pregnancy History of facial laser/procedure within 6 months History of topical retinoid, exfoliating agents within 6 months Allergy to botulinum toxin Open wound or infected wound in the treated area History of keloid scar History of photosensitivity or photoallergic reaction

Design outcomes

Primary

MeasureTime frame
Pore size 2 weeks, 1 month, 3 months, and 6 months after treatment Antera 3D camera, Visia CR camera, dermoscopic pictures

Secondary

MeasureTime frame
Skin oiliness 2 weeks, 1 month, 3 months, and 6 months after treatment Sebumeter

Countries

Thailand

Contacts

Public ContactNattaporn Sampattavanich

Siriraj Hospital

nariyata@gmail.com0813768622

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026